Costliest Drugs in England — NHS Prescribing Data
Medications ranked by total cost to the NHS over the last 12 months across all GP practices in England.
| # | Drug | Category | NHS Cost | Items |
|---|---|---|---|---|
| 1 | Dapagliflozin | Endocrine System | £322.1M | 8.9M |
| 2 | Beclometasone dipropionate | Respiratory System | £308.9M | 13.3M |
| 3 | Appliances | £293.0M | 3.8M | |
| 4 | Edoxaban | Cardiovascular System | £227.4M | 4.8M |
| 5 | Empagliflozin | Endocrine System | £163.5M | 4.3M |
| 6 | Semaglutide | Endocrine System | £145.6M | 1.6M |
| 7 | Sacubitril/valsartan | Cardiovascular System | £137.7M | 1.6M |
| 8 | Tirzepatide | Endocrine System | £137.2M | 1.3M |
| 9 | Budesonide | Respiratory System | £126.3M | 3.9M |
| 10 | Insulin aspart | Endocrine System | £111.5M | 2.6M |
| 11 | Influenza | Immunological Products and Vaccines | £111.0M | 9.2M |
| 12 | £104.7M | 2.1M | ||
| 13 | Colecalciferol | Nutrition and Blood | £103.9M | 28.2M |
| 14 | Omeprazole | Gastro-Intestinal System | £93.1M | 35.8M |
| 15 | Mesalazine (Systemic) | Gastro-Intestinal System | £89.1M | 1.6M |
| 16 | Insulin glargine | Endocrine System | £88.8M | 2.0M |
| 17 | Atorvastatin | Cardiovascular System | £87.9M | 73.2M |
| 18 | Rivaroxaban | Cardiovascular System | £86.8M | 4.3M |
| 19 | Estradiol | Endocrine System | £82.1M | 5.7M |
| 20 | Metformin hydrochloride | Endocrine System | £81.6M | 26.6M |
| 21 | Linagliptin | Endocrine System | £78.4M | 2.7M |
| 22 | Fluticasone propionate (Inhalation) | Respiratory System | £77.1M | 2.7M |
| 23 | Fluticasone/umeclidinium/vilanterol | Respiratory System | £74.8M | 1.5M |
| 24 | Glucose blood testing reagents | Endocrine System | £73.5M | 5.5M |
| 25 | Mirabegron | Obstetrics, Gynaecology and Urinary-Tract Disorders | £71.5M | 2.8M |
| 26 | Estradiol with progestogen | Endocrine System | £69.8M | 2.3M |
| 27 | Famotidine | Gastro-Intestinal System | £69.7M | 3.5M |
| 28 | Paracetamol | Central Nervous System | £67.5M | 15.9M |
| 29 | Macrogol 3350 | Gastro-Intestinal System | £63.0M | 7.4M |
| 30 | Appliances | £62.7M | 274.3K |